AppNote 260: Determination of PFAS in Water according to EN 17892 using online-SPE-LC-MS/MS


In the work presented here, the PFAS listed in EN 17892, including the substance list in EU Drinking Water Directive (EU 2020/2184), were determined by an automated method based on solid phase extraction with weak anion exchange sorbent combined with LC-MS/MS. Recovery rates, blank values, and limits of quantification (LOO) were determined following the requirements of the EN 17892 method. The method accuracy was demonstrated based on analysis of spiked water samples from different sources. LOQs in drinking water were below 0.5 ng/L for the vast majority of compounds.