Application Notes

Application Notes

AppNote 137: Stir Bar Sorptive Extraction (SBSE) and GC/MS Determination of Polar and Non-polar Drugs and Pharmaceuticals in Post Mortem Brain Tissue

Abstract

Stir Bar Sorptive Extraction (SBSE) is an innovative and efficient method for the extraction of drugs and pharmaceuticals from blood, urine and tissue samples in a forensic toxicology laboratory. As shown in this application note and earlier publications, SBSE is an effective screening tool for drugs and pharmaceuticals in biological fluids and tissue. The SBSE technique is easy to use and the method described in this publication is performed without additional use of organic solvents, centrifugation, or the liquid transfer steps that are normally necessary when performing liquid-liquid or solid-phase extraction.

Keywords

Drugs of abuse, Pharmaceuticals, Tissue samples, Stir Bar Sorptive Extraction (SBSE), Thermal Desorption Unit (TDU)