Applications

Automated Hydrolysis, Extraction and Analysis of Synthetic Cathinones in Urine using a Robotic Autosampler and LC-MS/MS Platform

AppNote 215/2020 Synthetic cathinones (also known as Bath Salts) are a group of drug compounds designated as Novel Psychoactive Substances (NPS). They are unregulated, mind-altering substances with no actual approved […]

Automating the Preparation of Matrix Matched Calibration Standards for the Analysis of Food Contaminants by LC/MS/MS

App Note 210/2020 The manual preparation of calibration standards and QC samples is part of the daily activities of laboratories that analyze food samples for contaminants. The accurate and precise […]

Quantification of Persistent Organic Pollutants in Dietary Supplements Using Stir Bar Sorptive Extraction Coupled with GC-MS/MS and Isotope Dilution Mass Spectrometry

App Note 214/2020 In this document we describe a method developed to quantify persistent organic pollutants (POPs) including polycyclic aromatic hydrocarbons (PAHs) and organochlorine pesticides (OCPs) in dietary supplements using […]

Highly Sensitive Determination of Contaminants in Surface Water in the Context of the EU Water Framework Directive using Stir Bar Sorptive Extraction (SBSE) and GC-MS/MS

App Note 196/2018 In the work presented here, highly sensitive determination of around 100 contaminants in surface water in the concentration range from low double digit to low triple-digit pg/L […]

Inlets for Capillary Gas Chromatography Users Guide

Identifying Key Odor Compounds in Bourbon Using Solvent-Free Aroma Dilution Analysis and a Novel Software for Interpreting GC-O Data

App Note 213/2020 Stir Bar Sorptive Extraction (SBSE) coupled with gas chromatography-mass spectrometry and olfactory detection (GC-MS/O) allows for separation and identification of aroma compounds in complex sample matrices with […]

Blood Alcohol Analysis Using an Automated Static Headspace Method

App Note 1/2005 Forensic laboratories face the need to analyze many samples of human blood and body fluids for alcohol content. The large number of samples that require quantification of […]

Stir Bar Sorptive Extraction Based on Restricted Access Material for the Direct Extraction of Drugs and Metabolites in Biological Fluids

App Note 5/2006 An experimental biocompatible stir bar sorptive extraction (SBSE) device was prepared using a restricted access material (RAM) as the SBSE coating. The biocompatible SBSE approach was advantageous […]

Automated Dynamic Headspace Sampling using Replaceable Sorbent Traps

App Note 1/2007 Static (equilibrium) headspace injection is commonly used for GC determination of volatiles in solid and liquid samples. Since this technique relies on the analyte partitioning between the […]

Minimizing Carryover Using a Four Solvent Wash Station

App Note 10/2008 When analytes from a sample injection into an LC system are not completely flushed from the sample introduction hardware, valve and connections following the injection, a carryover […]

Direct Thermal Extraction with Automated Liquid Calibration for the Quantification of Analytes in Solid Matrices

App Note 2/2008 Direct thermal extraction is a sensitive technique for the analysis of residual compounds in solid matrices such as polymers, films, powders, and fibers. This approach can be […]

Determination of 2-Methylisoborneol, Geosmin and 2,4,6-Trichloroanisole in Drinking Water by Dynamic Headspace Coupled to Selectable 1D/2D GC-MS with Simultaneous Olfactory Detection

App Note 1/2011 A method for the determination of trace amounts of off-flavor compounds such as 2-methylisoborneol (MIB), geosmin and 2,4,6-trichloroanisole (TCA) in drinking water is described based on dynamic […]