Feasibility of Extraction and Quantitation of Δ9-Tetrahydrocannabinol in Body Fluids by Stir Bar Sorptive Extraction (SBSE) and GC/MS


App Note 6/2005

This study demonstrates the feasibility of extracting THC from an aqueous matrix using Stir Bar Sorptive Extraction (SBSE) followed by thermal desorption into the injection port of a standard single quadrupole electron impact GC/MS to achieve detection limits less than 1.0 ng/mL. The specimen is diluted with water + methanol and extracted with a stir bar coated with a non-polar polydimethylsiloxane phase.