The GERSTEL Thermal Desorption Unit (TDU) was initially developed to be a dedicated instrument for use with GERSTEL Twister stir bars, but it is now used for 5 different sample introduction techniques. The TDU is used with the GERSTEL Cooled Injection System (CIS) on a GC or GC/MS system to enable ultra-trace analysis of a wide range of samples. The TDU mounts directly onto the CIS, eliminating the need for a transfer line. The TDU desorption liner mates directly with the glass inlet liner of the CIS—this novel liner-to-liner design prevents analytes from contacting active sites and thus provides a completely inert sample path. Prior to insertion of the desorption tube into the TDU, GC column head pressure is reduced to zero to prevent back-flush of sample or damage to the column. Transfer into the TDU is performed manually or automatically with the MPS 2 Twister Automation Option.